Odds, tips and predictions for the game San Francisco Giants vs San Diego Padres

The San Diego Padres (81-62) welcome the San Francisco Giants (69-73) to PETCO Park on Saturday for the 2nd game of their 3-game series. First pitch is scheduled for 8:40 p.m. ET. Let's check out FanDuel Sportsbook's odds around the Giants vs. Padres Opportunities and place your best bets with our expert MLB tips and predictions.

Season series: Draw 4-4

The Giants lost the series opener 5-1 on Friday and finished the season as a +180 underdog. San Francisco has now lost 5 of its last 6 games and has fallen to 4th place in the NL West. This season, they are 29-41 on the road and 66-76 against the spread (ATS). The Giants have lost 2 of 3 in their 2 previous series.

The Padres have been the opposite, winning 4 of their last 5 games. In the previous series, they beat the Detroit Tigers 2 of 3. San Diego has won 8 of its last 12 games. Their home record is 40-33 and their last 5 home games are 4-1. The Padres have an ATS of 73-70 this season.

Expected starters for Giants at Padres

RHP Logan Webb against RHP Dylan Cease

Webb (11-9, 3.43 ERA) is making his 30th start. He has a WHIP of 1.20, 2.2 BB/9 and 7.5 K/9 in 183 2/3 innings.

• Last start: Loss, 6 IP, 6 ER, 8 H, 0 BB, 4 K in the 7-5 home loss to the Miami Marlins on Sunday
• Away statistics 2024: 4-5, 4.29 ERA (86 IP, 41 ER), 1.44 WHIP, 8.3 K/9 in 15 starts
• Career against Padres: 3-2, 2.55 ERA (70 2/3 IP, 20 ER), 1.12 WHIP, 7.4 K/9 in 12 appearances (11 starts)

Cease (12-10, 3.62 ERA) is making his 30th start. He has a WHIP of 1.09, 3.2 BB/9 and 11.0 K/9 in 164 innings.

• Last start: No decision, 5 IP, 3 ER, 2 H, 3 BB, 4 K in the 4-3 away win against the Tampa Bay Rays on Sunday
• Home stats 2024: 5-6, 3.14 ERA (71 2/3 IP, 25 ER), 1.07 WHIP, 11.8 K/9 in 12 starts
• Career against Giants: 2-1, 2.61 ERA (20 2/3 IP, 6 ER), 1.11 WHIP, 10.9 K/9 in 4 starts

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Odds for Giants at Padres

Provided by FanDuel Sportsbook; visit the USA TODAY Sports Scores and Odds hub for a complete list. Odds last updated at 11:50 a.m. ET.

• Moneyline (ML): Giants +130 (bet $100 to win $130) | Padres -154 (bet $154 to win $100)
• Running Line (RL)/Against the Spread (ATS): Giants +1.5 (-184) | Padres -1.5 (+152)
• Over/Under (O/U): 7 (O: -110 | U: -110)

Tips and predictions for the game Giants vs Padres

forecast

Giants 5, Padres 3

Money line

BET GIANTS (+130).

The Giants have their ace on the mound and Webb has been a strong starting option for San Francisco. The Giants have a record of 5-2 in Webb's last 7 starts. The Giants also have a record of 40-32 after a loss, which is the case here.

The Padres have played well over the last week, but are only 5-4 in their last 9 games. They have also scored 4 or fewer points in 6 of those 9 games. For the value here, take GIANTS (+130).

Running Line/Against the Spread

HAPPEN.

There isn't much value here. The Giants are too expensive as an underdog, while the home team Padres are too risky as a favorite. Avoid this play.

Over/Under

BET OVER 7 (-110).

The Giants have reached Over in Webb's last 3 starts and are 3-2 O/W in their last 5 games. They have scored at least 4 goals in 3 of their last 5 games and allowed at least 6 in 3 of those games.

San Francisco has a record of 71-65-6 O/U this season. The Padres have a record of 3-3-1 O/U in their last 7 games and have a record of 76-64-3 O/U this season. Taking these trends into account, OVER 7 (-110).

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